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Recombinan Human Anti-CEA x Human Anti-Vγ9 Bispecific Antibody (Tandem scFv)  (CAT#: KN-0825-N69)

Recombinan Human Anti-CEA x Human Anti-Vγ9 Bispecific Antibody (Tandem scFv) is designed to be expressed as a scFv from an anti-CEA antibody variable domains fused with a scFv from an anti-Vγ9 antibody variable domains. It contains a His-tag at the C/N terminus for affinity purification. The BsAb exits as monomer in reducing and non-reducing conditions. This BsAb can retarget γδ T cells to CEA+ tumor cells . It is designed for the research of Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors therapy.
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Specifications

Targets
CEA & Vγ9
Type
Tandem scFv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Colorectal cancer (CRC); Gastric cancer; Pancreatic cancer; Lung cancer
Host Animal 1
Human
Host Animal 2
Human

Targets

Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
Vγ9
Gene ID
UniProt ID
Alternative Names
Vgamma9Vdelta2; TCR γ-chain; γ9 subunit of Vγ9Vδ2 TCR complex; High-affinity Vγ9-containing TCR; TRGV9; T cell receptor gamma variable 9; V2; TRGC1; TCRGV9
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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