Home > Products > CLDN18.2 & 4-1BB > Recombinant Human Anti-CLDN18.2 x Human Anti-4-1BB Bispecific Antibody (IgG(H)-scFv)

Recombinant Human Anti-CLDN18.2 x Human Anti-4-1BB Bispecific Antibody (IgG(H)-scFv)  (CAT#: KN-0825-N11)

Recombinant Human Anti-CLDN18.2 x Human Anti-4-1BB Bispecific Antibody (IgG(H)-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. The anti-4-1BB scFvs are fused to the C terminus of the anti-CLDN18.2 IgG-Fc chain. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can activate 4-1BB signaling, leading to T cell activation against CLDN18.2-overexpressing tumors. It is designed for the research of Solid tumors therapy.
Datasheet INQUIRY

Specifications

Targets
CLDN18.2 & 4-1BB
Type
IgG-scFv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors
Host Animal 1
Human
Host Animal 2
Human

Targets

Target 1
CLDN18.2
Gene ID
51208
UniProt ID
P56856
Alternative Names
Claudin18.2; CLDN18.2; CLDN18 splice variant 2; Claudin-18 isoform 2; Tight junction protein Claudin-18.2; CLDN18.2 protein; Claudin-18.2; SFTA5; SFTPJ; UNQ778; PRO1572; CLDN18; Claudin-18
Target 2
4-1BB
Gene ID
3604
UniProt ID
Q07011
Alternative Names
CD137; Cluster of Differentiation 137; 4-1BB; 4-1BB Receptor; ILA; Induced by Lymphocyte Activation; T-cell Antigen 4-1BB Homolog; CDw137; IMD109; 4-1BB ligand receptor; Tumor necrosis factor receptor superfamily member 9; T-cell antigen ILA
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
Online Inquiry

Related products of "CLDN18.2 & 4-1BB"
CLDN18.2 & 4-1BB Fab-scFv/sdAb-Fc

See other bsAb targets related to "4-1BB"

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-CLDN18.2 x Human Anti-4-1BB Bispecific Antibody (IgG(H)-scFv) (KN-0825-N11). Click the button below to contact us or submit your feedback about this product.

SERVICES

PRODUCTS

PLATFORMS

quality
ISO 9001 Certified - Creative Biolabs Quality Management System.
© 2026 Creative Biolabs. All Rights Reserved.