Recombinant Anti-CSF1 x Anti-IL34 Bispecific Antibody (Fab-scFv-Fc) (FABVC-143)

Recombinant Anti-CSF1 x Anti-IL34 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CSF1 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-IL34 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can bind two factors simultaneously. It is designed for the research of Myeloid pathogenic immunological diseases therapy.

Datasheet INQUIRY

Specifications

Targets

CSF1 & IL34

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Myeloid pathogenic immunological diseases

Targets

Target 1

CSF1

Gene ID

1435

UniProt ID

A0A024R0A1

Alternative Names

CSF1; colony stimulating factor 1 (macrophage); MCSF; CSF-1; macrophage colony-stimulating factor 1; lanimostim

Target 2

IL34

Gene ID

146433

UniProt ID

Q6ZMJ4

Alternative Names

IL-34; C16orf77; interleukin 34

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CSF1 x Anti-IL34 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-143)

Specifications

Targets

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