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Recombinant Anti-Csl x Anti-CD3 Bispecific Antibody (TandAb)  (TANDAB-H311)

Recombinant Anti-Csl x Anti-CD3 Bispecific Antibody (TandAb) is designed to be expressed as a monomeric subunit (single chain Diabody, scDb), with four variable domains from two parental antibodies. Then the two peptide chains can dimerize in a head-to-tail fashion. This BsAb can retarget T cells to tumor cells. It is designed for the research of Breast cancer; Glioma cancaer; Glioblastoma; Multiple myeloma (MM); Leukemia therapy.

Specifications
Targets
Csl & CD3
Type
TandAb
Species Reactivity
Human
Target 1
Csl
Host Animal 1
Human
Target 2
CD3
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Glioma cancaer; Glioblastoma; Multiple myeloma (MM); Leukemia
Targets
Target 1
Csl
Gene ID
UniProt ID
Alternative Names
SUH; csl; AOS3; CBF1; KBF2; RBP-J; RBPJK; IGKJRB; RBPSUH; IGKJRB1; recombination signal binding protein for immunoglobulin kappa J region; RBPJ; Lag-1; Suppressor of hairless
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
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