Name: Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-Fc-scFv)
SKU: BSTF-145
Rating: 5 (1 reviews)

Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CTLA4 scFv is fused to the N-terminus of Fc via a hinge region while another anti-GLUT2 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can bind two factors simultaneously. It is designed for the research of Renal cell cancer (RCC) therapy.

Datasheet INQUIRY

Specifications

Targets

CTLA4 & GLUT2

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Renal cell cancer (RCC)

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CTLA4

Gene ID

1493

UniProt ID

P16410

Alternative Names

CTLA4; cytotoxic T-lymphocyte-associated protein 4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; insulin-dependent diabetes mellitus 12; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4

Target 2

GLUT2

Gene ID

6514

UniProt ID

P11168

Alternative Names

SLC2A2; solute carrier family 2 (facilitated glucose transporter), member 2; GLUT2; solute carrier family 2, facilitated glucose transporter member 2; glucose transporter type 2, liver

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-145)

Specifications

Targets

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