Home > Products > DENV & CD64 > Recombinant Human Anti-DENV x Human Anti-CD64 Bispecific Antibody (F(ab')2-scFv2)

Recombinant Human Anti-DENV x Human Anti-CD64 Bispecific Antibody (F(ab')2-scFv2)  (BABFV-H316)

Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-DENV specificity is fused to the C terminus of the anti-CD64 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can retarget neutrophils cells to dengue virus. It is designed for the research of Dengue virus infection therapy.

Specifications

Targets
DENV & CD64
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Target 1
DENV
Host Animal 1
Human
Target 2
CD64
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Dengue virus infection

Targets

Target 1
DENV
Alternative Names
dengue virus; DENV; dengue fever; Flavivirus
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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