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Recombinant Human Anti-DENV x Human Anti-CD64 Bispecific Antibody (Fab-Fv)  (CAT#: FABFV-H316)

Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-DENV antibody are fused with the VL and VH domains of an anti-CD64 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can retarget neutrophils cells to dengue virus. It is designed for the research of Dengue virus infection therapy.
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Specifications

Targets
DENV & CD64
Type
Fab-Fv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Dengue virus infection

Targets

Target 1
DENV
Alternative Names
dengue virus; DENV; dengue fever; Flavivirus
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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