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Recombinant Anti-DENV x Anti-CD64 sdAb Bispecific Antibody (IgG-sdAb)  (CAT#: IGVHH-043)

Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (IgG-sdAb) is designed to be expressed as a LC and an extended HC with a sdAb linked to the C terminus. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget neutrophils cells to dengue virus. It is designed for the research of The Dengue virus infection therapy. As required, the sdAb can also be fused to the C terminus of the LC.
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Specifications

Targets
DENV & CD64
Type
IgG-sdAb
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Dengue virus infection
Host Animal 1
Mouse
Host Animal 2
llama

Targets

Target 1
DENV
Alternative Names
dengue virus; DENV; dengue fever; Flavivirus
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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