Name: Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (scFv-Fc-scFv)
SKU: BSTF-147
Rating: 5 (1 reviews)

Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-DENV scFv is fused to the N-terminus of Fc via a hinge region while another anti-CD64 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget neutrophils cells to dengue virus. It is designed for the research of Dengue virus infection therapy.

Datasheet INQUIRY

Specifications

Targets

DENV & CD64

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Dengue virus infection

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

DENV

Alternative Names

dengue virus; DENV; dengue fever; Flavivirus

Target 2

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-147)

Specifications

Targets

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