Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (scFv4-Ig) (FVTIG-147)

Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-DENV scFv is fused to the CH1 domain of a heavy chain and another anti-CD64 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can retarget neutrophils cells to dengue virus. It is designed for the research of Dengue virus infection therapy.

Datasheet INQUIRY

Specifications

Targets

DENV & CD64

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Dengue virus infection

Targets

Target 1

DENV

Alternative Names

dengue virus; DENV; dengue fever; Flavivirus

Target 2

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-147)

Specifications

Targets

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