Name: Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (sdAb-Fc-sdAb)
SKU: HCAB-043
Rating: 5 (1 reviews)

Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (sdAb-Fc-sdAb, Tetravalent Heavy Chain-only Antibody, Tetravalent HCAb) is symmetric protein with two pairs of single domain antibodies (sdAb), from anti-DENV and anti-CD64 antibodies, fused to the N-terminus and C-terminus of the Fc separately. This BsAb is bispecific, tetravelant, 2+2 antigen-binding valency. It can retarget neutrophils cells to dengue virus. It is designed for the research of The Dengue virus infection therapy.

Datasheet INQUIRY

Specifications

Targets

DENV & CD64

Type

sdAb-Fc-sdAb

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Dengue virus infection

Host Animal 1

llama

Host Animal 2

llama

Targets

Target 1

DENV

Gene ID

1956

UniProt ID

P00533

Alternative Names

EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

Target 2

CD64

Gene ID

4233

UniProt ID

A0A024R759

Alternative Names

MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (sdAb-Fc-sdAb) (CAT#: HCAB-043)

Specifications

Targets

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