Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Diabody-Fc) (BSDBF-H317)

Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-DKK1 and anti-SOST antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can bind two factors simultaneously and promote osteoblastogenesis. It is designed for the research of Osteoporosis; Osteogenesis imperfecta (OI); Low bone mineral density; Fracture therapy.

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Specifications

Targets

DKK1 & SOST

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Osteoporosis; Osteogenesis imperfecta (OI); Low bone mineral density; Fracture

Targets

Target 1

DKK1

Gene ID

27120

UniProt ID

Q9UK85

Alternative Names

DKKL1; dickkopf-like 1; SGY; CT34; SGY1; SGY-1; dickkopf-like protein 1; soggy; soggy-1; protein soggy-1; cancer/testis antigen 34

Target 2

SOST

Gene ID

50964

UniProt ID

Q9BQB4

Alternative Names

SOST; sclerostin; CDD; VBCH; SOST1; DAND6

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Diabody-Fc) (CAT#: BSDBF-H317)

Specifications

Targets

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