Home > Products > DKK1 & SOST > Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Fab-IgG)

Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Fab-IgG)  (FABIG-148)

Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can bind two factors simultaneously and promote osteoblastogenesis. It is designed for the research of Osteoporosis; Osteogenesis imperfecta (OI); Low bone mineral density; Fracture therapy.

Specifications

Targets
DKK1 & SOST
Type
Fab-IgG
Species Reactivity
Human
Target 1
DKK1
Host Animal 1
Mouse
Target 2
SOST
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Osteoporosis; Osteogenesis imperfecta (OI); Low bone mineral density; Fracture

Targets

Target 1
DKK1
Gene ID
UniProt ID
Alternative Names
DKKL1; dickkopf-like 1; SGY; CT34; SGY1; SGY-1; dickkopf-like protein 1; soggy; soggy-1; protein soggy-1; cancer/testis antigen 34
Target 2
SOST
Gene ID
UniProt ID
Alternative Names
SOST; sclerostin; CDD; VBCH; SOST1; DAND6

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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