Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (IgG-Fv) (BSGV-H317)

Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-DKK1 antibody variable domain is fused to the C terminal of an IgG of anti-SOST antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can bind two factors simultaneously and promote osteoblastogenesis. It is designed for the research of Osteoporosis; Osteogenesis imperfecta (OI); Low bone mineral density; Fracture therapy.

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Specifications

Targets

DKK1 & SOST

Type

IgG-Fv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Osteoporosis; Osteogenesis imperfecta (OI); Low bone mineral density; Fracture

Targets

Target 1

DKK1

Gene ID

27120

UniProt ID

Q9UK85

Alternative Names

DKKL1; dickkopf-like 1; SGY; CT34; SGY1; SGY-1; dickkopf-like protein 1; soggy; soggy-1; protein soggy-1; cancer/testis antigen 34

Target 2

SOST

Gene ID

50964

UniProt ID

Q9BQB4

Alternative Names

SOST; sclerostin; CDD; VBCH; SOST1; DAND6

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (IgG-Fv) (CAT#: BSGV-H317)

Specifications

Targets

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