Name: Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scFv4-Ig)
SKU: FVTIG-148
Rating: 5 (1 reviews)

Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-DKK1 scFv is fused to the CH1 domain of a heavy chain and another anti-SOST scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can bind two factors simultaneously and promote osteoblastogenesis. It is designed for the research of Osteoporosis; Osteogenesis imperfecta (OI); Low bone mineral density; Fracture therapy.

Datasheet INQUIRY

Specifications

Targets

DKK1 & SOST

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Osteoporosis; Osteogenesis imperfecta (OI); Low bone mineral density; Fracture

Targets

Target 1

DKK1

Gene ID

27120

UniProt ID

Q9UK85

Alternative Names

DKKL1; dickkopf-like 1; SGY; CT34; SGY1; SGY-1; dickkopf-like protein 1; soggy; soggy-1; protein soggy-1; cancer/testis antigen 34

Target 2

SOST

Gene ID

50964

UniProt ID

Q9BQB4

Alternative Names

SOST; sclerostin; CDD; VBCH; SOST1; DAND6

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-148)

Specifications

Targets

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