Name: Recombinant Anti-DLL4 x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2)
SKU: BABFV-149
Rating: 5 (1 reviews)

Recombinant Anti-DLL4 x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-DLL4 specificity is fused to the C terminus of the anti-VEGF Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

DLL4 & VEGF

Type

F(ab')2-scFv2

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Solid tumors

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

DLL4

Gene ID

54567

UniProt ID

Q9NR61

Alternative Names

DLL4; delta-like 4 (Drosophila); hdelta2; delta-like protein 4; delta like canonical Notch ligand 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-DLL4 x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-149)

Specifications

Targets

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