Home > Products > DLL4 & VEGF > Recombinant Human Anti-DLL4 x Human Anti-VEGF Bispecific Antibody (Fv-IgG)

Recombinant Human Anti-DLL4 x Human Anti-VEGF Bispecific Antibody (Fv-IgG)  (BSDG-H318)

Recombinant Anti-DLL4 x Anti-VEGF Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-DLL4 IgG with similar domains from an anti-VEGF antibody via short peptide linkers, or vice versa. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Solid tumors therapy.

Specifications

Targets
DLL4 & VEGF
Type
Appended IgGs
Species Reactivity
Human
Target 1
DLL4
Host Animal 1
Human
Target 2
VEGF
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors

Targets

Target 1
DLL4
Gene ID
UniProt ID
Alternative Names
DLL4; delta-like 4 (Drosophila); hdelta2; delta-like protein 4; delta like canonical Notch ligand 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

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