Home > Products > DLL4 & VEGF > Recombinant Human Anti-DLL4 x Human Anti-VEGF Bispecific Antibody (scDiabody-CH3)

Recombinant Human Anti-DLL4 x Human Anti-VEGF Bispecific Antibody (scDiabody-CH3)  (SCDBC-H318)

Recombinant Anti-DLL4 x Anti-VEGF Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-DLL4/anti-VEGF diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Solid tumors therapy.

Specifications
Targets
DLL4 & VEGF
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
DLL4
Host Animal 1
Human
Target 2
VEGF
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors
Targets
Target 1
DLL4
Gene ID
UniProt ID
Alternative Names
DLL4; delta-like 4 (Drosophila); hdelta2; delta-like protein 4; delta like canonical Notch ligand 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor
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