Home > Products > DLL4 & VEGF > Recombinant Human Anti-DLL4 x Human Anti-VEGF Bispecific Antibody (scFv-CH1/CL)

Recombinant Human Anti-DLL4 x Human Anti-VEGF Bispecific Antibody (scFv-CH1/CL)  (BSCC-H318)

Recombinant Anti-DLL4 x Anti-VEGF Bispecific Antibody (scFv-CH1/CL) is designed to be expressed as two chains. One scFv from an anti-DLL4 antibody variable domain is fused to CH1 and the other scFv from an anti-VEGF antibody variable domain fused to CL, or vice versa. And the CH1 and CL domains are linked covalently via a natural disulfide bond. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Solid tumors therapy.

Specifications

Targets
DLL4 & VEGF
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
DLL4
Host Animal 1
Mouse
Target 2
VEGF
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors

Targets

Target 1
DLL4
Gene ID
UniProt ID
Alternative Names
DLL4; delta-like 4 (Drosophila); hdelta2; delta-like protein 4; delta like canonical Notch ligand 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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