Recombinant Human Anti-DLL4 x Human Anti-VEGF Bispecific Antibody (scFv-Fc) (BSCFV-H318)

Recombinant Anti-DLL4 x Anti-VEGF Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-DLL4 specificity or anti-VEGF specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

DLL4 & VEGF

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Solid tumors

Targets

Target 1

DLL4

Gene ID

54567

UniProt ID

Q9NR61

Alternative Names

DLL4; delta-like 4 (Drosophila); hdelta2; delta-like protein 4; delta like canonical Notch ligand 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-DLL4 x Human Anti-VEGF Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-H318)

Specifications

Targets

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