Recombinant Anti-DR5 x Anti-FAP Bispecific Antibody (Bibody) is a Fab-scFv format that uses heterodimeric Fab as a scaffold, and a scFv region linked to one of its heavy (Fd) or light (L) chain. The scFv of the anti-DR5 specificity is fused to the anti-DR5 heavy or light chain of the Fab. This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.
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