Home > Products > DR5 & FAP > Anti-DR5 x Anti-FAP Bispecific Antibody (IgG-IgG)

Anti-DR5 x Anti-FAP Bispecific Antibody (IgG-IgG)  (BSIG-152)

Anti-DR5 x Anti-FAP Bispecific Antibody (IgG-IgG) is designed to be generated by crosslinking two full length IgGs, anti-DR5 and anti-FAP parental antibodies. A stable linkage is formed between the two antibodies. This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

Specifications
Targets
DR5 & FAP
Type
IgG-IgG
Species Reactivity
Human
Target 1
DR5
Host Animal 1
Mouse
Target 2
FAP
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer
Targets
Target 1
DR5
Gene ID
UniProt ID
Alternative Names
DR5; Death Receptor 5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; TNFRSF10B
Target 2
FAP
Gene ID
UniProt ID
Alternative Names
FAP; fibroblast activation protein, alpha; FAPA; SIMP; Fibroblast activation protein; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha; dipeptidyl peptidase FAP; surface-expressed protease; post-proline cleaving enzyme; gelatine degradation protease FAP; F19 cell surface antigen; integral membrane serine protease; serine integral membrane protease; 170 kDa melanoma membrane-bound gelatinase

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