Recombinant Anti-DR5 x Anti-FAP Bispecific Antibody (Tandem Fab) (BSFAB-152)

Recombinant Anti-DR5 x Anti-FAP Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-DR5 and anti-FAP parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

Datasheet

Specifications

Targets

DR5 & FAP

Type

Tandem Fab

Species Reactivity

Human

Target 1

DR5

Host Animal 1

Mouse

Target 2

FAP

Host Animal 2

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

Breast cancer; Ovary cancer; Colon cancer; Lung cancer

Targets

Target 1

DR5

Gene ID

8795

UniProt ID

O14763

Alternative Names

DR5; Death Receptor 5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; TNFRSF10B

Target 2

FAP

Gene ID

2191

UniProt ID

B4DLR2

Alternative Names

FAP; fibroblast activation protein, alpha; FAPA; SIMP; Fibroblast activation protein; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha; dipeptidyl peptidase FAP; surface-expressed protease; post-proline cleaving enzyme; gelatine degradation protease FAP; F19 cell surface antigen; integral membrane serine protease; serine integral membrane protease; 170 kDa melanoma membrane-bound gelatinase

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY

Online Inquiry

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

UK
167-169 Great Portland Street, 5th Floor, London, W1W 5PE
Tel: 44-207-097-1828
Email: