Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (F(ab')2-scFv2) (BABFV-153)

Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-DTPA specificity is fused to the C terminus of the anti-GD2 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

DTPA & GD2

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1

DTPA

Alternative Names

diethylenetriaminepentaacetic acid; DTPA; pentetic acid

Target 2

GD2

Alternative Names

Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-153)

Specifications

Targets

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