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Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Minibody)  (CAT#: MiniB-153)

Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Minibody) is designed to be expressed as the anti-DTPA scFv fused to N-terminus of Knob-CH3 domain and the anti-GD2 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors imaging and therapy.
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Specifications

Targets
DTPA & GD2
Type
Minibody
Species Reactivity
Human
Application
FuncS; Pretargeting system for radioimaging and radiotherapy
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1
DTPA
Alternative Names
diethylenetriaminepentaacetic acid; DTPA; pentetic acid
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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