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Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-153)
Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (scFv-CH3) contains two chains. The anti-DTPA scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-GD2 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors imaging and therapy.
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