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Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-155)
Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (scFv-CH3) contains two chains. The anti-EGFR scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-HER2 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Breast cancer; Colon cancer; Lung cancer; Pancreatic cancer; Gastric cancer; Solid tumors therapy.
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