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Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (scFv-IgG) (CAT#: BSSG-155)
Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-EGFR antibody variable domain are respectively connected to the N terminus of the anti-HER2 IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Breast cancer; Colon cancer; Lung cancer; Pancreatic cancer; Gastric cancer; Solid tumors therapy.
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