Recombinant Anti-EGFR x Anti-HER3 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-EGFR antibody are fused to the C terminus of an anti-HER3 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Solid tumors therapy.