Recombinant Anti-EGFR x Anti-HER3 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-EGFR specificity or anti-HER3 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Solid tumors therapy.
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