Name: Recombinant Human Anti-EGFR x Human Anti-HER3 Bispecific Antibody (scFv-Fc)
SKU: BSCFV-H323
Rating: 5 (1 reviews)

Recombinant Anti-EGFR x Anti-HER3 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-EGFR specificity or anti-HER3 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

EGFR & HER3

Type

scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Solid tumors

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

EGFR

Gene ID

1956

UniProt ID

P00533

Alternative Names

EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

Target 2

HER3

Gene ID

2065

UniProt ID

P21860

Alternative Names

ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; human epidermal growth factor receptor 3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-EGFR x Human Anti-HER3 Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-H323)

Specifications

Targets

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