Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (Bibody) is a Fab-VHH format that uses heterodimeric Fab as a scaffold, and a VHH region linked to one of its heavy (Fd) or light (L) chain. The VHH of the anti-IGF1R specificity is fused to the anti-EGFR heavy or light chain of the Fab. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Colorectal cancer; Cervical cancer; Breast cancer; Pancreatic cancer therapy.
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