Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (Miniantibody)  (MNAB-157)

Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-EGFR antibody variable domain is linked to another scFv of an anti-IGF1R antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Colorectal cancer; Cervical cancer; Breast cancer; Pancreatic cancer therapy.

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