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Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (sdAb-IgG) (CAT#: BSSG-399)
Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (sdAb-IgG) is formed by an IgG and two single domains antibodies (sdAbs). The sdAbs from an anti-MET antibody variable domain are respectively connected to the N terminus of the anti-EGFR IgG heavy chains or light chains to form sdAb-(H)IgG or sdAb-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Colorectal cancer; Pancreatic cancer; Head and neck cancer; Non-small cell lung cancer (NSCLC) therapy.
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