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Recombinant Anti-EGFR x Anti-PD1 Bispecific Antibody (Fab-IgG)  (FABIG-356)

Recombinant Anti-EGFR x Anti-PD1 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb is designed for the research of tumor therapy.

Specifications

Targets
EGFR & PD1
Type
Fab-IgG
Species Reactivity
Human
Target 1
EGFR
Host Animal 1
Mouse
Target 2
PD1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors

Targets

Target 1
EGFR
Gene ID
UniProt ID
Alternative Names
EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
Target 2
PD1
Gene ID
UniProt ID
Alternative Names
PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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