Recombinant Anti-EGFR x Anti-PD1 Bispecific Antibody (Tetravalent Heavy Chain-only Antibody) (HCAB-356)

Recombinant Anti-EGFR x Anti-PD1 Bispecific Antibody (HCAb) is a fusion protein of two sdAbs (VHHs) connected together by an Fc region. The sdAb (VHH) with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb is designed for the research of tumor therapy.

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Specifications

Targets

EGFR & PD1

Type

Tetravalent Heavy Chain-only Antibody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Solid tumors

Targets

Target 1

EGFR

Gene ID

1956

UniProt ID

P00533

Alternative Names

EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

Target 2

PD1

Gene ID

5133

UniProt ID

Q15116

Alternative Names

PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-EGFR x Anti-PD1 Bispecific Antibody (Tetravalent Heavy Chain-only Antibody) (CAT#: HCAB-356)

Specifications

Targets

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