Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-FAS antibody are fused with the VL and VH domains of an anti-CSPG4 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can induce targeted apoptosis. It is designed for the research of Melanoma therapy.