Home > Products > FAS & CSPG4 > Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (Fab-IgG)

Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (Fab-IgG)  (FABIG-H324)

Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can induce targeted apoptosis. It is designed for the research of Melanoma therapy.

Specifications
Targets
FAS & CSPG4
Type
Fab-IgG
Species Reactivity
Human
Target 1
FAS
Host Animal 1
Human
Target 2
CSPG4
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Melanoma
Targets
Target 1
FAS
Gene ID
UniProt ID
Alternative Names
APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; FAS; Fas cell surface death receptor
Target 2
CSPG4
Gene ID
UniProt ID
Alternative Names
NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG
Our services and products are only for lab research, not for any diagnostic or therapeutic use.

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