Home > Products > FAS & CSPG4 > Recombinant Human Anti-FAS x Human Anti-CSPG4 Bispecific Antibody (IgG(L)-scFv)

Recombinant Human Anti-FAS x Human Anti-CSPG4 Bispecific Antibody (IgG(L)-scFv)  (IGLFV-H325)

Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-FAS antibody are fused to the C terminus of an anti-CSPG4 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can induce targeted apoptosis. It is designed for the research of Melanoma therapy.

Specifications
Targets
FAS & CSPG4
Type
Appended IgGs
Species Reactivity
Human
Target 1
FAS
Host Animal 1
Human
Target 2
CSPG4
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Melanoma
Targets
Target 1
FAS
Gene ID
UniProt ID
Alternative Names
APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; FAS; Fas cell surface death receptor
Target 2
CSPG4
Gene ID
UniProt ID
Alternative Names
NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG
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