Home > Products > FAS & CSPG4 > Recombinant Human Anti-FAS x Human Anti-CSPG4 Bispecific Antibody (Miniantibody)

Recombinant Human Anti-FAS x Human Anti-CSPG4 Bispecific Antibody (Miniantibody)  (MNAB-H325)

Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-FAS antibody variable domain is linked to another scFv of an anti-CSPG4 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can induce targeted apoptosis. It is designed for the research of Melanoma therapy.

Specifications

Targets
FAS & CSPG4
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
FAS
Host Animal 1
Mouse
Target 2
CSPG4
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Melanoma

Targets

Target 1
FAS
Gene ID
UniProt ID
Alternative Names
APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; FAS; Fas cell surface death receptor
Target 2
CSPG4
Gene ID
UniProt ID
Alternative Names
NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG

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