Recombinant Human Anti-FAS x Human Anti-CSPG4 Bispecific Antibody (scFv-CH3) (BSFC-H325)

Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (scFv-CH3) contains two chains. The anti-FAS scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CSPG4 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can induce targeted apoptosis. It is designed for the research of Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

FAS & CSPG4

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Melanoma

Targets

Target 1

FAS

Gene ID

355

UniProt ID

P25445

Alternative Names

APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; FAS; Fas cell surface death receptor

Target 2

CSPG4

Gene ID

1464

UniProt ID

Q6UVK1

Alternative Names

NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-FAS x Human Anti-CSPG4 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-H325)

Specifications

Targets

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