Recombinant Human Anti-FAS x Human Anti-CSPG4 Bispecific Antibody (scFv-Fc) (BSCFV-H325)

Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-FAS specificity or anti-CSPG4 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can induce targeted apoptosis. It is designed for the research of Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

FAS & CSPG4

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Melanoma

Targets

Target 1

FAS

Gene ID

355

UniProt ID

P25445

Alternative Names

APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; FAS; Fas cell surface death receptor

Target 2

CSPG4

Gene ID

1464

UniProt ID

Q6UVK1

Alternative Names

NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-FAS x Human Anti-CSPG4 Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-H325)

Specifications

Targets

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