Name: Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (scFv4-Ig)
SKU: FVTIG-159
Rating: 5 (1 reviews)

Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-FAS scFv is fused to the CH1 domain of a heavy chain and another anti-CSPG4 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can induce targeted apoptosis. It is designed for the research of Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

FAS & CSPG4

Type

scFv4-Ig

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Melanoma

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

FAS

Gene ID

355

UniProt ID

P25445

Alternative Names

APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; FAS; Fas cell surface death receptor

Target 2

CSPG4

Gene ID

1464

UniProt ID

Q6UVK1

Alternative Names

NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-159)

Specifications

Targets

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