Name: Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (Tandem scFv-Fc)
SKU: BSFVF-159
Rating: 5 (1 reviews)

Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-FAS/CSPG4 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can induce targeted apoptosis. It is designed for the research of Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

FAS & CSPG4

Type

Tandem scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Melanoma

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

FAS

Gene ID

355

UniProt ID

P25445

Alternative Names

APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; FAS; Fas cell surface death receptor

Target 2

CSPG4

Gene ID

1464

UniProt ID

Q6UVK1

Alternative Names

NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (Tandem scFv-Fc) (BSFVF-159). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-FAS x Anti-CSPG4 Bispecific Antibody (Tandem scFv-Fc) (CAT#: BSFVF-159)

Specifications

Targets

Customer Reviews and Q&As