Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) (BABFV-160)

Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-FGF2 specificity is fused to the C terminus of the anti-VEGF Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Hepatocellular cancer (HCC); Breast cancer; Colon cancer; Lung cancer; Glioma cancer therapy.

Datasheet INQUIRY

Specifications

Targets

FGF2 & VEGF

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC); Breast cancer; Colon cancer; Lung cancer; Glioma cancer

Targets

Target 1

FGF2

Gene ID

2247

UniProt ID

P09038

Alternative Names

FGF; Fibroblast growth factor; FGF2; fibroblast growth factor 2; BFGF; FGFB; FGF-2; HBGF-2

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-160)

Specifications

Targets

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