Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-FGF2 IgG with similar domains from an anti-VEGF antibody via short peptide linkers, or vice versa. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Hepatocellular cancer (HCC); Breast cancer; Colon cancer; Lung cancer; Glioma cancer therapy.
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