Name: Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (scFv-CH3)
SKU: BSFC-160
Rating: 5 (1 reviews)

Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (scFv-CH3) contains two chains. The anti-FGF2 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-VEGF scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Hepatocellular cancer (HCC); Breast cancer; Colon cancer; Lung cancer; Glioma cancer therapy.

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Specifications

Targets

FGF2 & VEGF

Type

scFv-CH3

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC); Breast cancer; Colon cancer; Lung cancer; Glioma cancer

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

FGF2

Gene ID

2247

UniProt ID

P09038

Alternative Names

FGF; Fibroblast growth factor; FGF2; fibroblast growth factor 2; BFGF; FGFB; FGF-2; HBGF-2

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (scFv-CH3) (CAT#: BSFC-160)

Specifications

Targets

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