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Recombinant Human Anti-FGF2 x Human Anti-VEGF Bispecific Antibody (scFv-CH3)  (CAT#: BSFC-H326)

Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (scFv-CH3) contains two chains. The anti-FGF2 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-VEGF scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Hepatocellular cancer (HCC); Breast cancer; Colon cancer; Lung cancer; Glioma cancer therapy.
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Specifications

Targets
FGF2 & VEGF
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Hepatocellular cancer (HCC); Breast cancer; Colon cancer; Lung cancer; Glioma cancer

Targets

Target 1
FGF2
Gene ID
UniProt ID
Alternative Names
FGF; Fibroblast growth factor; FGF2; fibroblast growth factor 2; BFGF; FGFB; FGF-2; HBGF-2
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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