Home > Products > FGF2 & VEGF > Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (scFv-IgG)

Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (scFv-IgG)  (BSSG-160)

Recombinant Anti-FGF2 x Anti-VEGF Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-FGF2 antibody variable domain are respectively connected to the N terminus of the anti-VEGF IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Hepatocellular cancer (HCC); Breast cancer; Colon cancer; Lung cancer; Glioma cancer therapy.

Specifications

Targets
FGF2 & VEGF
Type
Appended IgGs
Species Reactivity
Human
Target 1
FGF2
Host Animal 1
Mouse
Target 2
VEGF
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Hepatocellular cancer (HCC); Breast cancer; Colon cancer; Lung cancer; Glioma cancer

Targets

Target 1
FGF2
Gene ID
UniProt ID
Alternative Names
FGF; Fibroblast growth factor; FGF2; fibroblast growth factor 2; BFGF; FGFB; FGF-2; HBGF-2
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

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