Home > Products > FGFR1 & KLB > Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Diabody-CH3)

Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Diabody-CH3)  (BSDBC-H327)

Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-FGFR1 and anti-KLB antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can bind two factors simultaneously and act as mimetic hormone (FGF21) . It is designed for the research of Type 2 diabetes therapy.

Specifications
Targets
FGFR1 & KLB
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
FGFR1
Host Animal 1
Human
Target 2
KLB
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Type 2 diabetes
Targets
Target 1
FGFR1
Gene ID
UniProt ID
Alternative Names
FGFR1; fibroblast growth factor receptor 1; CEK; FLG; HH2; OGD; ECCL; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; basic fibroblast growth factor receptor 1; HBGFR; FMS-like tyrosine kinase 2
Target 2
KLB
Gene ID
UniProt ID
Alternative Names
klotho beta; BKL; KLB; Beta-klotho; B-klotho; BetaKlotho; klotho beta like 3

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Heidenkampsweg 58, 20097 Hamburg, Germany
Tel: 44-207-097-1828
Email:
Related products of "FGFR1 & KLB"
45-1 Ramsey Road, Shirley, NY 11967, USA 1-631-381-2994 1-631-207-8356
24x7 CUSTOMER SERVICE
Easy access to products and services you need from our library via
powerful searching tools
© 2007 - 2020 Creative-Biolabs All Rights Reserved.
Distributors
To view the contact information for a specific location,
select your country or region: