Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Miniantibody) (MNAB-H327)

Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-FGFR1 antibody variable domain is linked to another scFv of an anti-KLB antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can bind two factors simultaneously and act as mimetic hormone (FGF21) . It is designed for the research of Type 2 diabetes therapy.

Datasheet INQUIRY

Specifications

Targets

FGFR1 & KLB

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Type 2 diabetes

Targets

Target 1

FGFR1

Gene ID

2260

UniProt ID

P11362

Alternative Names

FGFR1; fibroblast growth factor receptor 1; CEK; FLG; HH2; OGD; ECCL; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; basic fibroblast growth factor receptor 1; HBGFR; FMS-like tyrosine kinase 2

Target 2

KLB

Gene ID

152831

UniProt ID

Q86Z14

Alternative Names

klotho beta; BKL; KLB; Beta-klotho; B-klotho; BetaKlotho; klotho beta like 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Miniantibody) (MNAB-H327). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Miniantibody) (CAT#: MNAB-H327)

Specifications

Targets

Customer Reviews and Q&As